Flow stop device

ABSTRACT

Flow stop assemblies are described herein. A flow stop assembly configured to control flow through a tubing includes a flow stop base and a pincher. The flow stop base includes a base wall, at least one pincher guard, a tubing guide, a pincher recess, a pincher protrusion, and a base extension. The pincher is movable relative to the base extension and is configured to move between a flow position and an occlusion position, wherein in the flow position the pincher surface is spaced apart from the pincher protrusion and in the occlusion position, the pincher surface is disposed adjacent to the pincher protrusion and is configured to obstruct flow through the tubing.

CROSS REFERENCE TO RELATED APPLICATION

This application is a continuation of U.S. patent application Ser. No.16/597,734, entitled “FLOW STOP DEVICE,” filed Oct. 9, 2019, thedisclosure of which is incorporated herein by reference in its entirety.

FIELD OF THE INVENTION

The present disclosure generally relates to flow control devices, and,in particular, to flow control devices for tubing.

BACKGROUND

Medical treatments often include the infusion of a medical fluid (e.g.,a saline solution or a liquid medication) to patients using anintravenous (IV) catheter that is connected though an arrangement offlexible tubing and fittings, commonly referred to as an “IV set,” to asource of fluid, for example, an IV bag. During use, the flow of medicalfluid through tubing may be occluded with pinch clamps to control theflow of the medical fluid. Often, pinch clamps are designed for aspecific tube size.

In some applications, variations in tube size may hinder the performanceof the pinch clamp.

SUMMARY

The disclosed subject matter relates to flow stop assemblies. In certainembodiments, a flow stop assembly is disclosed that is configured tocontrol flow through a tubing and comprises a flow stop base, and apincher. The flow stop base includes a base wall extending from the flowstop base; at least one pincher guard extending from the base wall,wherein the at least one pincher guard is configured to be disposedaround the tubing; a tubing guide configured to receive the tubing,wherein the at least one pincher guard and the tubing guide are axiallyspaced apart and are configured to axially align the tubing through theflow stop base; a pincher recess defined between the base wall, the atleast one pincher guard, and the tubing guide; a pincher protrusiondisposed within the pincher recess and configured to be adjacent to thetubing, wherein the pincher protrusion extends from the base wall; and abase extension extending away from the pincher recess. The pincher ismovable relative to the base extension and comprises a pincher surface,the pincher configured to move between a flow position and an occlusionposition, wherein in the flow position the pincher surface is spacedapart from the pincher protrusion and in the occlusion position, thepincher surface is disposed adjacent to the pincher protrusion and isconfigured to obstruct flow through the tubing.

In certain embodiments, a flow stop assembly is disclosed that comprisesa tubing defining a flow path, a flow stop base, and a pincher. The flowstop base includes a base wall extending from the flow stop base; atleast one pincher guard extending from the base wall, wherein the atleast one pincher guard is configured to be disposed around the tubing;a tubing guide configured to receive the tubing, wherein the at leastone pincher guard and the tubing guide are axially spaced apart and areconfigured to axially align the tubing through the flow stop base; apincher recess defined between the base wall, the at least one pincherguard, and the tubing guide; a pincher protrusion disposed within thepincher recess and configured to be adjacent to the tubing, wherein thepincher protrusion extends from the base wall; and a base extensionextending away from the pincher recess. The pincher is movable relativeto the base extension and comprises a pincher surface, the pincherconfigured to move between a flow position and an occlusion position,wherein in the flow position the pincher surface is spaced apart fromthe pincher protrusion and in the occlusion position, the pinchersurface is disposed adjacent to the pincher protrusion and is configuredto obstruct flow through the tubing.

In certain embodiments, a method is disclosed that comprises providingfluid flow through a tubing; actuating a pincher against the tubing tofold the tubing over a pincher protrusion; and obstructing the fluidflow through the tubing.

It is understood that various configurations of the subject technologywill become readily apparent to those skilled in the art from thedisclosure, wherein various configurations of the subject technology areshown and described by way of illustration. As will be realized, thesubject technology is capable of other and different configurations andits several details are capable of modification in various otherrespects, all without departing from the scope of the subjecttechnology. Accordingly, the summary, drawings and detailed descriptionare to be regarded as illustrative in nature and not as restrictive.

BRIEF DESCRIPTION OF THE DRAWINGS

The accompanying drawings, which are included to provide furtherunderstanding and are incorporated in and constitute a part of thisspecification, illustrate disclosed embodiments and together with thedescription serve to explain the principles of the disclosedembodiments. In the drawings:

FIG. 1 is a perspective view of a flow stop assembly in a flow position,in accordance with various aspects of the present disclosure.

FIG. 2 is a reverse perspective view of the flow stop assembly of FIG. 1in the flow position, in accordance with various aspects of the presentdisclosure.

FIG. 3 is a perspective view of a flow stop assembly in an occlusionposition, in accordance with various aspects of the present disclosure.

FIG. 4 is an elevation view of the flow stop assembly of FIG. 3 in theocclusion position, in accordance with various aspects of the presentdisclosure.

FIG. 5 is a perspective view of a flow stop assembly in a flow position,in accordance with various aspects of the present disclosure.

FIG. 6 is a perspective view of a flow stop assembly, in accordance withvarious aspects of the present disclosure.

FIG. 7 is a perspective view of a flow stop assembly, in accordance withvarious aspects of the present disclosure.

DETAILED DESCRIPTION

The disclosed flow stop assembly incorporates a pinching mechanism tofold tubing and occlude fluid flow therethrough. The pincher can bemovable to fold the tubing over a pincher protrusion. By folding thetubing, flow within the tubing can be reliably occluded when using awide variety of tubing sizes.

The detailed description set forth below is intended as a description ofvarious configurations of the subject technology and is not intended torepresent the only configurations in which the subject technology may bepracticed. The detailed description includes specific details for thepurpose of providing a thorough understanding of the subject technology.However, it will be apparent to those skilled in the art that thesubject technology may be practiced without these specific details. Insome instances, well-known structures and components may be shown inblock diagram form in order to avoid obscuring the concepts of thesubject technology. Like components are labeled with identical elementnumbers for ease of understanding. Reference numbers may have lettersuffixes appended to indicate separate instances of a common elementwhile being referred to generically by the same number without a suffixletter.

While the following description is directed to the occlusion of medicalfluid during the administration of medical fluid using the disclosedflow stop assembly, it is to be understood that this description is onlyan example of usage and does not limit the scope of the claims. Variousaspects of the disclosed flow stop assembly may be used in anyapplication where it is desirable to control the flow of fluid.

The disclosed flow stop assembly overcomes several challenges discoveredwith respect to certain conventional clamps. One challenge with certainconventional clamps is that certain conventional clamps are designed tobe used with specific tubing sizes. Because variations in tubing sizesmay hinder the performance of conventional clamps or require varioussizes of conventional clamps, the use of conventional clamps isundesirable.

Therefore, in accordance with the present disclosure, it is advantageousto provide a flow stop assembly as described herein that allows for flowocclusion with a wide variety of tubing sizes. The disclosed flow stopassembly provides a folding mechanism that allows for reliable flowocclusion for a wide variety of tubing sizes.

An example of a flow stop assembly that allows for reliable flowocclusion is now described.

FIG. 1 is a perspective view of a flow stop assembly 100 in a flowposition, in accordance with various aspects of the present disclosure.In the depicted example, the flow stop assembly 100 controls the flow offluids such as medical fluids as they are delivered from a fluid sourceto a patient. As illustrated, medical fluid can be directed through aflow path defined by tubing 102. As can be appreciated, the tubing 102can be of any suitable diameter needed for treatment.

During operation, the occlusion mechanism of the flow stop assembly 100can be actuated to allow for fluid flow to be permitted or occluded byfolding the tubing 102 to occlude flow therethrough. As illustrated, aportion of the tubing 102 passes through the flow stop base 110 to allowthe flow stop assembly 100 to control flow through the tubing 102.

In some embodiments, tubing 102 extends through, and is axially alignedand/or retained by a pincher guard 114 and a tubing guide 112. In theillustrated embodiment, pincher guards 114 extend from a base wall 111on either side of the tubing 102. The base wall 111 can extendvertically from the flow stop base 110 and include a rib to facilitatecoupling with other components. The pincher guards 114 can preventlateral movement of the tubing 102 during operation, including duringpinching or occlusion operations.

A lower portion of the tubing 102 can pass through a tubing guide 112formed in the flow stop base 110. The tubing guide 112 can be acylindrical member configured to receive the tubing 102. The tubingguide 112 can be sized to prevent radial movement of the tubing 102while allowing axial movement of the tubing 102. The tubing guide 112and the pincher guard 114 can cooperatively axially align the tubing102. In certain embodiments, the tubing 102 can be axially affixed orcoupled within the tubing guide 112. As can be appreciated, the tubingguide 112 can be spaced apart from the pincher guards 114 to define apincher recess 116 wherein the tubing 102 extends across the pincherrecess 116. Further, the base wall 111 can define the pincher recess 116and also prevent or restrict radial movement of the tubing 102.

In a flow position, the flow path defined within the tubing 102 isunobstructed to allow the flow of medical fluid. In some embodiments,the pincher surface 142 of the pincher 140 is spaced apart from theportion of the tubing 102 disposed within the pincher recess 116. Asillustrated, the pincher 140 is rotated away from the tubing 102disposed within the pincher recess 116. As described herein, the pincher140 can rotate on a guide pin 144 disposed within a guide slot 122formed within the base extension 120 of the flow stop base 110. Asillustrated, the base extension 120 extends away from the pincher recess116 of the flow stop base 110. The pincher 140, in some instances, canfurther translate along the guide slot 122. In some embodiments, thegeometry of the guide slot 122 can determine the range of permittedtravel of the pincher 140.

In the depicted example, the pincher 140 can be actuated or rotated by amechanical or planar linkage, such as a three bar linkage or a four barlinkage. As illustrated, the pincher 140 can be actuated by rotating ormoving the rocker 130. The rocker 130 can be rotatably coupled to thebase extension 120 of the flow stop base 110. As illustrated, the rocker130 can rotate about a rocker pivot 132 rotatably coupling the rocker130 to the base extension 120. As the rocker 130 is rotated, the rocker130 can actuate the pincher 140 to rotate and/or translate the pincher140. In some embodiments, the rocker 130 can be rotatably coupled to thepincher 140 at a pincher link 134. During operation, the rocker 130 canbe actuated by a clinician to actuate or rotate the pincher 140.

FIG. 2 is a reverse perspective view of the flow stop assembly 100 ofFIG. 1 in the flow position, in accordance with various aspects of thepresent disclosure. During operation, the rotation of the rocker 130 andtherefore the pincher 140 can be limited to prevent damage to the tubing102 or to the flow stop assembly 100. In the depicted example, therocker 130 can include a clamping limit wall 136 that extends from therocker 130 to engage the base extension 120 at a rotational limit. Forexample, the clamping limit wall 136 can be configured to engage withthe base extension 120 at a rotational position of the rocker 130determined to effectively occlude or clamp the tubing 102 withoutdamaging the tubing 102. Further, the clamping limit wall 136 mayprovide tactile and/or auditory feedback to the clinician.

FIG. 3 is a perspective view of a flow stop assembly 100 in an occlusionposition, in accordance with various aspects of the present disclosure.FIG. 4 is an elevation view of the flow stop assembly 100 of FIG. 3 inthe occlusion position, in accordance with various aspects of thepresent disclosure. With reference to FIGS. 3 and 4 , in an occlusionposition or configuration, the flow stop assembly 100 can occlude theflow of medical fluid through the tubing 102. Advantageously, the flowstop assembly 100 can be utilized to occlude the flow of medical fluidduring an infusion procedure or any other suitable procedure.

In the depicted example, the pincher 140 is actuated to engage thepincher surface 142 against the tubing 102 to fold the tubing 102 into afolded position 104 over the pincher protrusion 118 formed within thepincher recess 116. As illustrated, the pincher protrusion 118 extendsfrom the base wall 111. By folding or kinking the tubing 102 over thepincher protrusion 118, the flow within the tubing 102 can be occludedor obstructed to limit or stop fluid flow through the tubing 102.

During operation, to move from a flow position to an occlusion position,the pincher 140 is rotated or otherwise actuated into place. As thepincher surface 142 engages the tubing 102, the pincher guards 114, basewall 111, and/or the tubing guide 112 that define the pincher recess 116prevent undesired radial movement of the tubing 102 during engagement.

In some embodiments, the rocker 130 is rotated to rotate and/ortranslate the pincher 140 into the occlusion position. As illustrated,the rocker 130 is rotated to be in line with the base extension 120 torotate the pincher 140 toward the pincher recess 116 and fold the tubing102 over the pincher protrusion 118. Advantageously, by utilizing therocker 130 or linkage, a clinician can easily fold the tubing 102 overthe pincher protrusion 118 with minimal force.

FIG. 5 is a perspective view of a flow stop assembly 200 in a flowposition, in accordance with various aspects of the present disclosure.In the depicted example, the flow stop assembly 200 can utilize atranslating or sliding pincher 240 to fold or occlude the tubing 202.

During operation, the pincher 240 can slide from a flow position to anocclusion position. In the occlusion position, the pincher surface 242of the pincher 240 can engage with the tubing 202 to fold the tubing 202over the pincher protrusion 218 as described herein.

In some embodiments, the pincher 240 can utilize a linkage to translatethe pincher 240 from the flow position to the occlusion position. Forexample, the flow stop assembly 200 can utilize a four bar linkage toactuate the pincher 240. In the depicted example, the pincher 240 can beconstrained to translational movement.

As illustrated, a crank 230 and a rocker 250 can cooperatively allow forthe translation of the pincher 240. In some embodiments, the crank 230is rotatably coupled to the base extension 220 of the flow stop base210. As illustrated, the crank 230 can rotate about a crank pivot 232rotatably coupling the crank 230 to the base extension 220. As the crank230 is rotated, the crank 230 can actuate the rocker 250. In someembodiments, the crank 230 can be rotatably coupled to the rocker 250 ata rocker link 234. In the depicted example, the rotation of the crank230 can actuate or otherwise rotate the rocker 250. During operation,the cooperative rotation of the crank 230 and the rocker 250 provides atranslation force to the pincher 240 to translate the pincher 240 asdesired.

During operation, the rotation of the crank 230 and therefore thetranslation of the pincher 240 can be limited to prevent damage to thetubing 202 or to the flow stop assembly 200. In the depicted example,the crank 230 can include a clamping limit wall 236 that extends fromthe crank 230 to engage the base extension 220 at a rotational limit.For example, the clamping limit wall 236 can be configured to engagewith the base extension 220 at a rotational position of the crank 230determined to effectively occlude or clamp the tubing 202 withoutdamaging the tubing 202. Further, the clamping limit wall 236 mayprovide tactile and/or auditory feedback to the clinician.

FIG. 6 is a perspective view of a flow stop assembly 300, in accordancewith various aspects of the present disclosure. In the depicted example,the flow stop assembly 300 can utilize a rotating cam or pincher 340 tofold or occlude the tubing.

During operation, the pincher 340 can rotate and/or slide from a flowposition to an occlusion position. In the occlusion position, thepincher surface 342 of the pincher 340 can engage with the tubing (notpictured) to fold the tubing over the pincher protrusion 318 asdescribed herein.

In some embodiments, the pincher 340 can utilize a cam mechanism torotate the pincher 340 from the flow position to the occlusion position.In the depicted example, the pincher 340 can rotate and/or translate.

As illustrated, a crank portion 330 of the pincher 340 and a rocker 350can cooperatively allow for the translation of the pincher 340. In someembodiments, the crank portion 330 rotatably couples the pincher 340 tothe base extension 320 of the flow stop base 310. As illustrated, thecrank portion 330 can rotate about a crank pivot 332 rotatably couplingthe pincher 340 to the base extension 320. As the crank portion 330 isrotated, the pincher 340 can actuate the rocker 350. In someembodiments, the pincher 340 can have a cam surface disposed opposite tothe pincher surface 342 that engages with a cam surface of the rocker350 such that the rotation of the pincher 340 can actuate or otherwiserotate the rocker 350. During operation, the cooperative rotation of thepincher 340 and the rocker 350 provides a translation force to thepincher 340 to translate the pincher 340 as desired.

During operation, the rotation of the crank portion 330 and thereforethe translation of the pincher 340 can be limited to prevent damage tothe tubing or to the flow stop assembly 300. In the depicted example,the pincher 340 can include a clamping limit wall 336 that extends fromthe crank portion 330 to engage the cap 314 at a rotational limit. Forexample, the clamping limit wall 336 can be configured to engage withthe cap 314 at a rotational position of the pincher 340 determined toeffectively occlude or clamp the tubing without damaging the tubing.Further, the clamping limit wall 336 and the cap 314 may provide tactileand/or auditory feedback to the clinician.

Optionally, the cap 314 can be disposed over the pincher 340 and/or therocker 350 to at least partially cover the components of the flow stopassembly 300. In some embodiments, a pincher guard or upper tubing guide312 formed through the cap 314 can retain and/or align tubing thatpasses through the flow stop assembly 300, functioning as a pincherguard as described with respect to other embodiments described herein.As illustrated, the upper tubing guide 312 can be a tubular protrusionor cylindrical member that extends axially from the cap 314 to form apartial sleeve around the tubing. The upper tubing guide 312 can preventlateral or radial movement of tubing during operation, including duringpinching or occlusion operations. The upper tubing guide 312 can besized to prevent radial movement of the tubing while allowing axialmovement of the tubing.

FIG. 7 is a perspective view of a flow stop assembly 400, in accordancewith various aspects of the present disclosure. In the depicted example,the flow stop assembly 400 can utilize a rotating pincher 440 to fold orocclude the tubing.

During operation, the pincher 440 can rotate from a flow position to anocclusion position. In the occlusion position, the pincher surface 442of the pincher 440 can engage with the tubing (not pictured) to fold thetubing over the pincher protrusion 418 as described herein.

In some embodiments, the pincher 440 is rotatably coupled to the baseextension 420 of the flow stop base 410. As illustrated, the pincher 440can rotate about a pivot 432 allowing the pincher surface 442 to travelalong an arc. During operation, the rotation of the pincher 440 aboutthe pivot 432 can provide a mechanical advantage to the clinician.

During operation, the rotation of the pincher 440 can be limited toprevent damage to the tubing or to the flow stop assembly 400. In thedepicted example, the pincher 440 can include a clamping limit wall 436that extends from the pincher 440 to engage the cap 414 at a rotationallimit. For example, the clamping limit wall 436 can be configured toengage with the cap 414 at a rotational position of the pincher 440determined to effectively occlude or clamp the tubing without damagingthe tubing. Further, the clamping limit wall 436 and the cap 414 mayprovide tactile and/or auditory feedback to the clinician.

Optionally, the cap 414 can be disposed over the pincher 440 to at leastpartially cover and/or retain the components of the flow stop assembly400. In some embodiments, a pincher guard or upper tubing guide 412formed through the cap 414 can retain and/or align tubing that passesthrough the flow stop assembly 400, functioning as a pincher guard asdescribed with respect to other embodiments described herein. Asillustrated, the upper tubing guide 412 can be a tubular protrusion orcylindrical member that extends axially from the cap 414 to form apartial sleeve around the tubing. The upper tubing guide 412 can preventlateral or radial movement of tubing during operation, including duringpinching or occlusion operations. The upper tubing guide 412 can besized to prevent radial movement of the tubing while allowing axialmovement of the tubing.

Optionally, the flow stop assembly 400 can include a tubing coupler 413that is retained and aligned within pincher recess 416. Duringoperation, portions of tubing can be fluidly coupled to the tubingcoupler 413 allowing fluid communication therethrough. As can beappreciated, flow through the tubing coupler 413 can be stopped by thepinching or occlusion operation as described herein. Advantageously, bycoupling tubing to the tubing coupler, aligning and/or positioningtubing within the flow stop assembly 400 can be simplified.

The present disclosure is provided to enable any person skilled in theart to practice the various aspects described herein. The disclosureprovides various examples of the subject technology, and the subjecttechnology is not limited to these examples. Various modifications tothese aspects will be readily apparent to those skilled in the art, andthe generic principles defined herein may be applied to other aspects.

A reference to an element in the singular is not intended to mean “oneand only one” unless specifically so stated, but rather “one or more.”Unless specifically stated otherwise, the term “some” refers to one ormore. Pronouns in the masculine (e.g., his) include the feminine andneuter gender (e.g., her and its) and vice versa. Headings andsubheadings, if any, are used for convenience only and do not limit theinvention.

The word “exemplary” is used herein to mean “serving as an example orillustration.” Any aspect or design described herein as “exemplary” isnot necessarily to be construed as preferred or advantageous over otheraspects or designs. In one aspect, various alternative configurationsand operations described herein may be considered to be at leastequivalent.

A phrase such as an “aspect” does not imply that such aspect isessential to the subject technology or that such aspect applies to allconfigurations of the subject technology. A disclosure relating to anaspect may apply to all configurations, or one or more configurations.An aspect may provide one or more examples. A phrase such as an aspectmay refer to one or more aspects and vice versa. A phrase such as an“embodiment” does not imply that such embodiment is essential to thesubject technology or that such embodiment applies to all configurationsof the subject technology. A disclosure relating to an embodiment mayapply to all embodiments, or one or more embodiments. An embodiment mayprovide one or more examples. A phrase such an embodiment may refer toone or more embodiments and vice versa. A phrase such as a“configuration” does not imply that such configuration is essential tothe subject technology or that such configuration applies to allconfigurations of the subject technology. A disclosure relating to aconfiguration may apply to all configurations, or one or moreconfigurations. A configuration may provide one or more examples. Aphrase such a configuration may refer to one or more configurations andvice versa.

In one aspect, unless otherwise stated, all measurements, values,ratings, positions, magnitudes, sizes, and other specifications that areset forth in this specification, including in the claims that follow,are approximate, not exact. In one aspect, they are intended to have areasonable range that is consistent with the functions to which theyrelate and with what is customary in the art to which they pertain.

In one aspect, the term “coupled” or the like may refer to beingdirectly coupled. In another aspect, the term “coupled” or the like mayrefer to being indirectly coupled.

Terms such as “top,” “bottom,” “front,” “rear” and the like if used inthis disclosure should be understood as referring to an arbitrary frameof reference, rather than to the ordinary gravitational frame ofreference. Thus, a top surface, a bottom surface, a front surface, and arear surface may extend upwardly, downwardly, diagonally, orhorizontally in a gravitational frame of reference.

Various items may be arranged differently (e.g., arranged in a differentorder, or partitioned in a different way) all without departing from thescope of the subject technology. All structural and functionalequivalents to the elements of the various aspects described throughoutthis disclosure that are known or later come to be known to those ofordinary skill in the art are expressly incorporated herein by referenceand are intended to be encompassed by the claims. Moreover, nothingdisclosed herein is intended to be dedicated to the public regardless ofwhether such disclosure is explicitly recited in the claims. No claimelement is to be construed under the provisions of 35 U.S.C. § 112,sixth paragraph, unless the element is expressly recited using thephrase “means for” or, in the case of a method claim, the element isrecited using the phrase “step for.” Furthermore, to the extent that theterm “include,” “have,” or the like is used, such term is intended to beinclusive in a manner similar to the term “comprise” as “comprise” isinterpreted when employed as a transitional word in a claim.

The Title, Background, Summary, Brief Description of the Drawings andAbstract of the disclosure are hereby incorporated into the disclosureand are provided as illustrative examples of the disclosure, not asrestrictive descriptions. It is submitted with the understanding thatthey will not be used to limit the scope or meaning of the claims. Inaddition, in the Detailed Description, it can be seen that thedescription provides illustrative examples and the various features aregrouped together in various embodiments for the purpose of streamliningthe disclosure. This method of disclosure is not to be interpreted asreflecting an intention that the claimed subject matter requires morefeatures than are expressly recited in each claim. Rather, as thefollowing claims reflect, inventive subject matter lies in less than allfeatures of a single disclosed configuration or operation. The followingclaims are hereby incorporated into the Detailed Description, with eachclaim standing on its own as a separately claimed subject matter.

The claims are not intended to be limited to the aspects describedherein, but is to be accorded the full scope consistent with thelanguage claims and to encompass all legal equivalents. Notwithstanding,none of the claims are intended to embrace subject matter that fails tosatisfy the requirement of 35 U.S.C. § 101, 102, or 103, nor should theybe interpreted in such a way.

What is claimed is:
 1. A flow stop assembly configured to control flowthrough a tubing, the flow stop assembly comprising: a flow stop baseconfigured to receive the tubing, the flow stop base defining a guideslot; a pincher movable relative to the flow stop base and comprising apincher surface and a guide pin extending through the guide slot, thepincher configured to move between a flow position and an occlusionposition, wherein in the flow position the pincher surface is spacedapart from the tubing and in the occlusion position, the pincher surfaceis disposed in contact with the tubing and is configured to obstructflow through the tubing; and a rocker rotatably coupled to the flow stopbase and the pincher, wherein rotation of the rocker moves the pincherand the pincher is rotatable about the rocker in a first rotational axisand the guide pin in a second rotational axis different from the firstrotational axis.
 2. The flow stop assembly of claim 1, wherein therocker comprises a clamping limit wall extending from the rocker, theclamping limit wall configured to limit the rotation of the rocker. 3.The flow stop assembly of claim 1, wherein rotation of the rockerrotates the pincher.
 4. The flow stop assembly of claim 1, furthercomprising: a crank rotatably coupled to the rocker, wherein rotation ofthe crank moves the pincher.
 5. The flow stop assembly of claim 4,wherein the crank comprises a clamping limit wall extending from thecrank, the clamping limit wall configured to limit the rotation of thecrank and the movement of the pincher.
 6. The flow stop assembly ofclaim 1, wherein the pincher is translatable about the guide slot. 7.The flow stop assembly of claim 1, wherein the flow stop base comprisesa tubing guide configured to receive the tubing and is configured toaxially align the tubing through the flow stop base.
 8. A flow stopassembly, comprising: a tubing defining a flow path; a flow stop baseconfigured to receive the tubing, the flow stop base defining a guideslot; a pincher rotatable relative to the flow stop base and comprisinga pincher surface and a guide pin extending through the guide slot, thepincher configured to move between a flow position and an occlusionposition, wherein in the flow position the pincher surface is spacedapart from the tubing and in the occlusion position, the pincher surfaceengages the tubing to fold the tubing to obstruct the flow path of thetubing; and a rocker rotatably coupled to the flow stop base and thepincher, wherein rotation of the rocker moves the pincher and thepincher is rotatable about the rocker in a first rotational axis and theguide pin in a second rotational axis different from the firstrotational axis.
 9. The flow stop assembly of claim 8, wherein therocker comprises a clamping limit wall extending from the rocker, theclamping limit wall configured to limit the rotation of the rocker. 10.The flow stop assembly of claim 8, wherein rotation of the rockerrotates the pincher.
 11. The flow stop assembly of claim 8, furthercomprising: a crank rotatably coupled to the rocker, wherein rotation ofthe crank translates the pincher.
 12. The flow stop assembly of claim11, wherein the crank comprises a clamping limit wall extending from thecrank, the clamping limit wall configured to limit the rotation of thecrank and the translation of the pincher.
 13. The flow stop assembly ofclaim 8, wherein the pincher is translatable about the guide slot. 14.The flow stop assembly of claim 8, wherein the flow stop base comprisesa tubing guide configured to receive the tubing and is configured toaxially align the tubing through the flow stop base.
 15. A method,comprising: providing fluid flow through a tubing, wherein the tubingextends through a flow stop base defining a guide slot; rotating arocker in a first rotational axis and the guide slot in a secondrotational axis different than the first rotational axis to actuate apincher against the tubing to fold the tubing over a pincher protrusion;and obstructing the fluid flow through the tubing.
 16. The method ofclaim 15, further comprising rotating the pincher to engage against thetubing.
 17. The method of claim 15, further comprising sliding thepincher to engage against the tubing.
 18. The method of claim 15,further comprising limiting an actuation range of the pincher.
 19. Themethod of claim 15, further comprising translating the pincher about theguide slot.
 20. The method of claim 15, further comprising: receivingthe tubing in a tubing guide of the flow stop base; and axially aligningthe tubing through the flow stop base.